Motorists are being advised to expect delays on the M74 north and southbound between Raith, Junction 5, and Maryville, Junction 4.
Work is set to take place from April 2 for approximately eight days as part of the £500m M8 M73 M74 Motorway Improvements Project.
A stretch of the M74 between Bothwell and Uddingston will be reduced from three lanes to two lanes in each direction. The closure of lane three is to allow crossover points to be constructed between the north and south carriageways.
Once constructed, the crossover points will enable M74 traffic to travel in contraflow while overhead gantries are removed. The removal of the gantries will enable the carriageway to be widened by an extra lane in both directions.
This traffic management is required to ensure the safety of road users and the workforce whilst these works are being carried out.
Access to the M73 and M74 Junction 4 Maryville and M74 J5 Raith will be maintained, although delays are expected.
Graeme Reid, Project Manager for the M8 M73 M74 Motorway Improvements Project, said: “These works are taking place concurrently with several other major traffic management schemes, including the M73 between Maryville and Baillieston and Raith, Junction 5.
“We are advising motorists to refer to the Transport Scotland and Traffic Scotland websites for live traffic updates and to plan their journeys in advance.”