Motherwell residents have launched a campaign to stop 100 houses being built in the grounds of the former Strathclyde Hospital.
They say the land was gifted to the townspeople by the Duke of Hamilton and shouldn’t be the site of new homes.
People who attended a public meeting at Dalziel High School also expressed concern about increased traffic and pollution should a development get the go-ahead.
Their fears have been raised at the same time as another developer says it wants to build 100 houses at the former bus depot in nearby Tinkers Lane.
Last year housebuilder Barratt was given planning permission for 66 homes there, but nothing has been built and now Springfield Homes has revealed plans for a bigger development.
Three years ago Sainsburys was refused planning permission to build a supermarket at the former bus depot.
An action group has been formed to fight development at the Strathclyde Hospital site after Bellway Homes informed nearby residents of its plans.
A spokesman said: “We’re concerned at the extra traffic and pollution, with two access roads proposed from Crawford Street and one from Airbles Road.
“Airbles Road and Hamilton Road are hugely congested as it is. People are also worried at the impact on the Dalziel High School roll.
“Apart from all that, we believe the land the hospital was built on was given to the people of Motherwell for their welfare by the Duke of Hamilton.
“There are 260 trees on the site and, while we appreciate something has to be done, we would like it retained as green space for the people, perhaps as an extension to the Duchess of Hamilton Park.”
A planning application has not yet been lodged, but protestors are to meet council officials to voice concerns.